The combination of neural stem cells and nerve growth factor (NGF)/ Ganglioside monalsialate (GM1) achieves good results in the treatment of Autism

by Drs. Like Wu, Xiaojuan Wang, Bo Cheng, Susan Chu, Shengjie Liu and Xiang Wang

Wu Medical Center, Bejing, China

Autism is a disorder of neural development characterized by impaired social interaction and verbal and non-verbal communication, and by restricted, repetitive or stereotyped behavior. The diagnostic criteria require that symptoms become apparent before a child is three years old. Autism affects information processing in the brain by altering how nerve cells and their synapses connect and organize; it is unknown how this occurs. It is one of three recognized disorders in the autism spectrum (ASDs), the other two being Asperger syndrome, which lacks delay in cognitive development and language, and pervasive developmental disorder, not otherwise specified (commonly abbreviated as PDD-NOS), which is the diagnosis when the full set of criteria for autism or Asperger syndrome are not met.
Parents usually notice signs in the first two years of their child's life. The signs usually develop gradually, but some autistic children first begin to develop normally and then regress. Early behavioral, cognitive, or speech interventions can help autistic children gain self-care, social, and communication skills. Not many children with autism live independently after reaching adulthood, though some become successful. An autistic culture has developed, with some individuals seeking a cure and others believing autism should be accepted as a difference and not treated as a disorder.

Autism is a highly variable neurodevelopmental disorder that first appears during infancy or childhood, and generally follows a steady course without remission. Overt symptoms gradually begin after the age of six months, become established by the age of two or three, and tend to continue through adulthood, although often in a more muted form. It is distinguished not by a single symptom, but by a characteristic triad of symptoms: impairments in social interaction; impairments in communication; and restricted interests and repetitive behavior. Other aspects, such as atypical eating, are also common but are not essential for diagnosis.

Autism's individual symptoms occur in the general population and appear not to be highly related, and it lacks a clear line separating pathologically severe from common traits.
There is no specific drug to treat autism. Special education and training curriculum system can improve prognosis. With the increased study of autism, we have gradually realized that autism is a diffuse developmental disorder of the central nervous system, which falls under certain genetic factors, and is caused by the stimulation of various kinds of environmental factors. All kinds of genetic factors and environmental factors interfere with the normal development of the nervous system. The patient may have less normally functional nerve cells in the brain than other children of the same age. There has been significant stagnation in growth in many encephalic regions. After many years of study, the Wu Stem Cell Medical Center (WSCMC) found that restarting the nervous system development of the brain is important to treat autism. The WSCMC used neural stem cell implants, in addition to unique stem cell regulation techniques for the body, in order to enable the implanted neural stem cells to reach the target organs and restart the development of specific nerve cells in the brain. Meanwhile, the combined application of drug therapy including Nerve growth factor (NGF) plus Ganglioside monalsialate (GM1) enhances the function of the implanted neural stem cells. This can significantly improve the symptoms of autism, and improve the environmental communication skills and self-care ability required in daily life.

Related Information:

• Autism Patient Stories